I think I'm going to like this new system (I've got the hardcovers on pre-order already, so I don't feel guilty for snagging the PDF's). The wizard took me forever to figure out, simply because I went into it looking for spell lists and per day charts, and didn't find any. When it finally clicked I was amazed at the simplicity and effectiveness. From the little I've seen, I do think that there needs to be more spell options, however; it looks like wizards may start getting a bit cookie-cutter after a while, imo.
Attacks vs. Saves are an interesting concept as well--one that I think will work well once you're used to it. There are so many different attack options for each class though, I'm afraid it may get a bit confusing at first just deciding on which to use.
In any case, I'm looking forward to playing and, more importantly, creating with the new rules. It promises to be an adventure!