Yes this can be done, I have a GE plug in for my own world.
It has the various layers for political boundaries, countries, population centers, even place markers for each Story Arc in the campaign.
Now the bad news.
I have no idea how to do this, I hired someone do it for me.
I will give a word of caution that it takes a LOT of mapping to pull this off. A high quality high res image at continent view when zoomed in gets very pixilated. There is a way of adding additional images on top to simulate the same way you drill down on GE but each of those maps needs to be created and linked correctly.
I attached a sample so you can see what I mean prior to attaching any additional images. DSWorld.zip