Okay, so I got the lakes working, thanks Ascension! I wouldn't have thought to use cloud brushes for lakes, but it totally makes sense now.

Click image for larger version. 

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I think I'm going to keep this as a base map for my Shadow of Yesterday games, but go through and add cities, towns, and travel markers as the players journey around the world.

Thanks for all the suggestions and comments. Looking forward to putting a new map up some time.