I've been stuck on my laptop without a USB mouse before. Sure, if you're just casually using your laptop (or computer with EvoMouse, or anything else that requires you abrate your finger on a not-perfectly-smooth surface) it probably won't bother you. But I'm a gamer, I do my cartography and various other projects, and I work from a computer, so all in all I spend almost twelve hours a day using a mouse. I think by hour six I'd be looking for fingertip replacements like the guitarist from Black Sabbath.