As a artistically-challenged individual, I offer my standard advice: make sure that you can already do on a piece of paper with a standard writing implement what you want to use the expensive device for. My experience (argued against by some individuals here) is that new hardware won't magically make things better; it's the practice that makes things better. I offer this advice mainly due to my own intolerance for frustration. I have spent a great deal of time and dollars looking for a tool and toy that will help me to improve the appearance of my output. So far, it hasn't worked for me (again, others have had different experience because the fancy toy has made them push past where I would have quit).
Having said that, I would also caution about the size of such a device. If you don't have a solid way to mount it to your working surface. Monitors are often trickier to rotate to get a good working angle than is a pad of paper because they are usually fixed to a stand in some way. At 11 pounds, this beastie is something that you are likely not going to be picking up and moving around lightly. As always, it depends on your style of use. If you're used to working on similar-sized pads on a easel, this would probably work well. If you're more of a sketchpad sort of person, it might take some getting used to.
This particular device has a battery-powered stylus, so you want to make sure to keep those things charged at all times (and possibly invest in an extra one or two that you rotate through the charger to keep everything charged). It really sucks to have the device stop working when you're fully engaged in your task and have to stop in the middle of it and recharge something.
The reviews are pretty good, but it's new enough that there's not a lot to say about longevity. If I had some of that artistic talent stuff, I might invest in one of these.