short answer... most likely, but it depends what you mean by large. per pixel operations get slow very quick. you may also find that with such a large image the rivers will be fairly thin. depending on what you are trying to do they may not be to your taste.
Photoshop, CC3, ArcGIS, Bryce, Illustrator, Maptool
And on every 5th cycle it travels across the internet and makes Waldronate coffee -- he really likes coffee
Dollhouse Syndrome = The temptation to turn a map into a picture, obscuring the goal of the image with the appeal of cute, or simply available, parts. Maps have clarity through simplification.
--- Sigurd
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